TX2-121-1

Modify Date: 2024-01-16 18:39:06

TX2-121-1 Structure
TX2-121-1 structure
 Common Name TX2-121-1
CAS Number 1603845-42-6 Molecular Weight 716.931
Density N/A Boiling Point N/A
Molecular Formula C42H52N8O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TX2-121-1


TX2-121-1 is a bivalent hydrophobically tagged adamantane derivative of TX1-85-1, a potent, selective, ATP-competitive Her3 (ErbB3) inhibitor; induces degradation and interferences with Her2/Her3 and c-Met/Her3 interactions, prevents Her3 heterodimerization, induces preferential death of Her3-dependent cell lines with an EC50 in the range of 0.8-1.4 uM.

 Names

Name TX2-121-1

 TX2-121-1 Biological Activity

Description TX2-121-1 is a bivalent hydrophobically tagged adamantane derivative of TX1-85-1, a potent, selective, ATP-competitive Her3 (ErbB3) inhibitor; induces degradation and interferences with Her2/Her3 and c-Met/Her3 interactions, prevents Her3 heterodimerization, induces preferential death of Her3-dependent cell lines with an EC50 in the range of 0.8-1.4 uM.
References References 1. Xie T, et al. Nat Chem Biol. 2014 Dec;10(12):1006-12. View Related Products by Target EGFR

 Chemical & Physical Properties

Molecular Formula C42H52N8O3
Molecular Weight 716.931
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Chemsrc provides TX2-121-1(CAS#:1603845-42-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TX2-121-1 are included as well.>> amp version: TX2-121-1

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