Glicoricone

Modify Date: 2025-08-25 17:40:01

Glicoricone Structure
Glicoricone structure
Common Name Glicoricone
CAS Number 161099-37-2 Molecular Weight 368.38
Density N/A Boiling Point N/A
Molecular Formula C21H20O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Glicoricone


Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity[1][2].

 Names

Name Glicoricone

 Glicoricone Biological Activity

Description Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity[1][2].
Related Catalog
Target

IC50: 140 μM (monoamine oxidase)[1]

References

[1]. Hatano T, et, al. Phenolic constituents of licorice. III. Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase. Chem Pharm Bull (Tokyo). 1991 May;39(5):1238-43.

[2]. Boonmuen N, et, al. Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids. 2016 Jan;105:42-9.

 Chemical & Physical Properties

Molecular Formula C21H20O6
Molecular Weight 368.38
InChIKey SSDIPYMSXRNGMZ-UHFFFAOYSA-N
SMILES COc1c(CC=C(C)C)c(O)cc(O)c1-c1coc2cc(O)ccc2c1=O
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