KBP-7018 hydrochloride

Modify Date: 2025-09-06 12:10:53

KBP-7018 hydrochloride Structure
KBP-7018 hydrochloride structure
Common Name KBP-7018 hydrochloride
CAS Number 1613437-67-4 Molecular Weight 575.06
Density N/A Boiling Point N/A
Molecular Formula C31H31ClN4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KBP-7018 hydrochloride


A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF).

 Names

Name KBP-7018 hydrochloride

 KBP-7018 hydrochloride Biological Activity

Description A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF).
References References 1. Huang Z, et al. ACS Med Chem Lett. 2017 Sep 30;8(11):1142-1147. 2. Huang Z, et al. Drug Des Devel Ther. 2015 Aug 5;9:4319-28. View Related Products by Target c-Kit

 Chemical & Physical Properties

Molecular Formula C31H31ClN4O5
Molecular Weight 575.06
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