EPZ015866(GSK591)
Modify Date: 2024-01-08 11:00:01
EPZ015866(GSK591) structure
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Common Name | EPZ015866(GSK591) | ||
|---|---|---|---|---|
| CAS Number | 1616391-87-7 | Molecular Weight | 380.483 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 648.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C22H28N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 345.9±31.5 °C | |
Use of EPZ015866(GSK591)EPZ015866 is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 22 nM. |
| Name | 2-(Cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]isonicotinamide |
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| Synonym | More Synonyms |
| Description | EPZ015866 is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 22 nM. |
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| Related Catalog | |
| Target |
IC50: 22 nM (PRMT5)[1] |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 648.4±55.0 °C at 760 mmHg |
| Molecular Formula | C22H28N4O2 |
| Molecular Weight | 380.483 |
| Flash Point | 345.9±31.5 °C |
| Exact Mass | 380.221222 |
| LogP | 3.66 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.645 |
| Storage condition | -20℃ |
| 4-Pyridinecarboxamide, 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]- |
| 2-(Cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]isonicotinamide |
| GSK591 |
| EPZ015866 |
| EPZ-015866 |