2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D

Modify Date: 2025-09-10 19:19:20

2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Structure
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D structure
Common Name 2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D
CAS Number 162049-83-4 Molecular Weight 487.38300
Density N/A Boiling Point N/A
Molecular Formula C20H20F3N3O8 Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Names

Name 2-((3-Trifluoromethyl)phenyl)histamine dimaleate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C20H20F3N3O8
Molecular Weight 487.38300
Exact Mass 487.12000
PSA 203.90000
LogP 2.72060
InChIKey GGDUVPKRZGATLR-SPIKMXEPSA-N
SMILES NCCc1cnc(-c2cccc(C(F)(F)F)c2)[nH]1.O=C(O)C=CC(=O)O.O=C(O)C=CC(=O)O

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H301-H315-H318-H335
Precautionary Statements P261-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T: Toxic;
Risk Phrases R25
Safety Phrases S26
RIDADR UN 2811 6.1/PG 3

 Articles4

More Articles
Synthesis and histamine H1 receptor agonist activity of a series of 2-phenylhistamines, 2-heteroarylhistamines, and analogues.

J. Med. Chem. 38 , 1287-1294, (1995)

New histamine derivatives characterized by a (substituted) aryl, heteroaryl, benzyl, or heteroarylmethyl substituent in the C2 position of the imidazole ring have been prepared from appropriate imidat...

Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion.

Invest. Ophthalmol. Vis. Sci. 53(6) , 2993-3003, (2012)

The purpose of this study was to determine the effect of histamine and its receptors on goblet cell secretion.Cultured rat and human goblet cells were grown in RPMI 1640. Goblet cell secretion of high...

Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor.

J. Pharmacol. Exp. Ther. 305 , 1104-1115, (2003)

Species isoforms of histamine H2-, H3-, and H4-receptors differ in their pharmacological properties. The study aim was to dissect differences between the human H1R (hH1R) and guinea pig H1R (ghH1R). W...

 Synonyms

(2-[2-(3-Trifluoromethyl)phenyl)-1H-imidazol-4-yl]ethanamine dimaleate Compound 39
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D
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