GSK'481
Modify Date: 2025-08-21 22:29:28
GSK'481 structure
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Common Name | GSK'481 | ||
|---|---|---|---|---|
| CAS Number | 1622849-58-4 | Molecular Weight | 377.393 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 677.0±55.0 °C at 760 mmHg | |
| Molecular Formula | C21H19N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 363.2±31.5 °C | |
Use of GSK'481GSK'481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cellsGSK'481 have approximately equivalent RIP1 FP potencies against human andcynomolgus monkey RIP1 but was >100-fold less potent against nonprimate RIP1 |
| Name | gsk481 |
|---|---|
| Synonym | More Synonyms |
| Description | GSK'481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cellsGSK'481 have approximately equivalent RIP1 FP potencies against human andcynomolgus monkey RIP1 but was >100-fold less potent against nonprimate RIP1 |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 677.0±55.0 °C at 760 mmHg |
| Molecular Formula | C21H19N3O4 |
| Molecular Weight | 377.393 |
| Flash Point | 363.2±31.5 °C |
| Exact Mass | 377.137543 |
| PSA | 84.67000 |
| LogP | 2.06 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.653 |
| Storage condition | -20℃ |
| 3-Isoxazolecarboxamide, 5-(phenylmethyl)-N-[(3S)-2,3,4,5-tetrahydro-5-methyl-4-oxo-1,5-benzoxazepin-3-yl]- |
| 5-Benzyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide |
| GSK481a |
| GSK-481 |
| (S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)isoxazole-3-carboxamide |
| GSK'481 |