LY3202626

Modify Date: 2024-10-03 10:12:19

LY3202626 Structure
LY3202626 structure
Common Name LY3202626
CAS Number 1628690-73-2 Molecular Weight 498.508
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C22H20F2N8O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY3202626


LY3202626 is a small molecule non-selective BACE1 inhibitor, causes dose-dependent reductions in CSF and plasma Aβ concentrations, shows potential for the treatment of Alzheimer's disease. Alzheimer Disease Phase 2 Clinical

 Names

Name N-{3-[(4aR,7aS)-2-Amino-6-(5-fluoro-2-pyrimidinyl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-4-fluorophenyl}-5-methoxy-2-pyrazinecarboxamide
Synonym More Synonyms

 LY3202626 Biological Activity

Description LY3202626 is a small molecule non-selective BACE1 inhibitor, causes dose-dependent reductions in CSF and plasma Aβ concentrations, shows potential for the treatment of Alzheimer's disease. Alzheimer Disease Phase 2 Clinical
References References View Related Products by Target Beta-secretase (BACE) Alzheimer Disease

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C22H20F2N8O2S
Molecular Weight 498.508
Exact Mass 498.139801
LogP 3.08
Index of Refraction 1.750

 Synonyms

2-Pyrazinecarboxamide, N-[3-[(4aR,7aS)-2-amino-6-(5-fluoro-2-pyrimidinyl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-4-fluorophenyl]-5-methoxy-
N-{3-[(4aR,7aS)-2-Amino-6-(5-fluoro-2-pyrimidinyl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-4-fluorophenyl}-5-methoxy-2-pyrazinecarboxamide
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