(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide

Modify Date: 2024-01-14 11:01:30

(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide Structure
(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide structure
Common Name (E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide
CAS Number 1632320-78-5 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C12H10N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide


F8-S43-S3 is an inhibitor of SARS-CoV-2 main protease, with an IC50 of 9.69 μM[1].

 Names

Name 5-(4-nitrophenyl)-2-furaldehyde thiosemicarbazone
Synonym More Synonyms

  Biological Activity

Description F8-S43-S3 is an inhibitor of SARS-CoV-2 main protease, with an IC50 of 9.69 μM[1].
Related Catalog
References

[1]. Dou X, et, al. Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main protease. Eur J Med Chem. 2022 Aug 5;238:114508.

 Chemical & Physical Properties

Molecular Formula C12H10N4O3S

 Synonyms

Hydrazinecarbothioamide, 2-[[5-(4-nitrophenyl)-2-furanyl]methylene]-, (2E)-
5-(4-nitrophenyl)-2-furaldehyde thiosemicarbazone
(2E)-2-{[5-(4-Nitrophenyl)-2-furyl]methylene}hydrazinecarbothioamide
MFCD00695942
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