(R)-Ezetimibe

Modify Date: 2024-01-05 12:31:02

(R)-Ezetimibe Structure
(R)-Ezetimibe structure
Common Name (R)-Ezetimibe
CAS Number 163380-16-3 Molecular Weight 409.425
Density 1.3±0.1 g/cm3 Boiling Point 654.9±55.0 °C at 760 mmHg
Molecular Formula C24H21F2NO3 Melting Point N/A
MSDS N/A Flash Point 349.9±31.5 °C

 Names

Name (4S)-1-(4-fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 654.9±55.0 °C at 760 mmHg
Molecular Formula C24H21F2NO3
Molecular Weight 409.425
Flash Point 349.9±31.5 °C
Exact Mass 409.148956
PSA 60.77000
LogP 3.26
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.624

 Synthetic Route

~%

(R)-Ezetimibe Structure

(R)-Ezetimibe

CAS#:163380-16-3

Literature: US2006/69080 A1, ; Page/Page column 27 ;

~%

(R)-Ezetimibe Structure

(R)-Ezetimibe

CAS#:163380-16-3

Literature: US2005/96307 A1, ; Page/Page column 24 ;

~%

(R)-Ezetimibe Structure

(R)-Ezetimibe

CAS#:163380-16-3

Literature: Journal of Medicinal Chemistry, , vol. 41, # 6 p. 973 - 980

~%

(R)-Ezetimibe Structure

(R)-Ezetimibe

CAS#:163380-16-3

Literature: Journal of Medicinal Chemistry, , vol. 41, # 6 p. 973 - 980

~%

(R)-Ezetimibe Structure

(R)-Ezetimibe

CAS#:163380-16-3

Literature: Journal of Medicinal Chemistry, , vol. 41, # 6 p. 973 - 980

~%

(R)-Ezetimibe Structure

(R)-Ezetimibe

CAS#:163380-16-3

Literature: Journal of Medicinal Chemistry, , vol. 41, # 6 p. 973 - 980

~%

(R)-Ezetimibe Structure

(R)-Ezetimibe

CAS#:163380-16-3

Literature: Journal of Medicinal Chemistry, , vol. 41, # 6 p. 973 - 980

~%

(R)-Ezetimibe Structure

(R)-Ezetimibe

CAS#:163380-16-3

Literature: Journal of Medicinal Chemistry, , vol. 41, # 6 p. 973 - 980

 Synonyms

1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone
2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-
(3’R)-Ezetimibe;(3R,4S)-1-(4-Fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone;EzetiMibe (3R)-IsoMer;(R)-EzetiMibe
Ezetimibe Impurity 2