Auristatin F

Modify Date: 2024-01-29 06:30:18

Auristatin F Structure
Auristatin F structure
Common Name Auristatin F
CAS Number 163768-50-1 Molecular Weight 745.989
Density 1.1±0.1 g/cm3 Boiling Point 894.4±65.0 °C at 760 mmHg
Molecular Formula C40H67N5O8 Melting Point N/A
MSDS N/A Flash Point 494.7±34.3 °C

 Use of Auristatin F


Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.

 Names

Name auristatin F
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 894.4±65.0 °C at 760 mmHg
Molecular Formula C40H67N5O8
Molecular Weight 745.989
Flash Point 494.7±34.3 °C
Exact Mass 745.498962
PSA 157.82000
LogP 4.99
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.523
Storage condition 2-8℃

 Synonyms

Auristatin F
N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide
L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-
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