Ethyl 5-methyl-1H-indole-2-carboxylate

Modify Date: 2024-01-13 17:54:59

Ethyl 5-methyl-1H-indole-2-carboxylate Structure
Ethyl 5-methyl-1H-indole-2-carboxylate structure
Common Name Ethyl 5-methyl-1H-indole-2-carboxylate
CAS Number 16382-15-3 Molecular Weight 203.237
Density 1.2±0.1 g/cm3 Boiling Point 356.5±22.0 °C at 760 mmHg
Molecular Formula C12H13NO2 Melting Point 162-164°C
MSDS Chinese USA Flash Point 169.4±22.3 °C

 Use of Ethyl 5-methyl-1H-indole-2-carboxylate


It is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.

 Names

Name Ethyl 5-methylindole-2-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 356.5±22.0 °C at 760 mmHg
Melting Point 162-164°C
Molecular Formula C12H13NO2
Molecular Weight 203.237
Flash Point 169.4±22.3 °C
Exact Mass 203.094635
PSA 42.09000
LogP 3.56
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.609

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Substituent Effects in the Fischer Indolization of (2-Sulfonyloxyphenyl) hydrazones (Fischer Indolization and Related Compounds. XXX). Murakami Y, et al.

Chem. Pharm. Bull. 47 , 791-97, (1999)

 Synonyms

Ethyl 5-Methylindole-2-Carboxylate
Ethyl 5-methyl-1H-indole-2-carboxylate
MFCD00022703
1H-Indole-2-carboxylic acid, 5-methyl-, ethyl ester
5-Methylindole-2-carboxylic acid ethyl ester