PLX7922

Modify Date: 2025-09-11 19:15:33

PLX7922 structure	Common Name	PLX7922
	CAS Number	1638772-61-8	Molecular Weight	464.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₅FN₆O₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PLX7922

PLX7922, a RAF inhibitor, can bind with BRAFV600E. PLX7922 inhibits pERK in BRAFV600E cell lines, and activates pERK in mutant NRAS cell lines[1].

Name	PLX7922

Description	PLX7922, a RAF inhibitor, can bind with BRAFV600E. PLX7922 inhibits pERK in BRAFV600E cell lines, and activates pERK in mutant NRAS cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	RAF[1]
In Vitro	PLX7922 (1-1000 nM) inhibits pERK in BRAFV600E cell lines, activates pERK in mutant NRAS cell lines (B9 and IPC-298)[1].
References	[1]. Zhang C, et, al. RAF inhibitors that evade paradoxical MAPK pathway activation. Nature. 2015 Oct 22;526(7574):583-6.

Molecular Formula	C₂₀H₂₅FN₆O₂S₂
Molecular Weight	464.58
InChIKey	YBUJMZKTOUBMGW-UHFFFAOYSA-N
SMILES	CCN(C)S(=O)(=O)Nc1cccc(-c2nc(C(C)(C)C)sc2-c2ccnc(N)n2)c1F

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PLX7922
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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