Longiferone B

Modify Date: 2024-01-30 11:19:45

Longiferone B Structure
Longiferone B structure
Common Name Longiferone B
CAS Number 1639810-67-5 Molecular Weight 218.33
Density 1.0±0.1 g/cm3 Boiling Point 309.5±22.0 °C at 760 mmHg
Molecular Formula C15H22O Melting Point N/A
MSDS N/A Flash Point 138.7±13.2 °C

 Use of Longiferone B


Longiferone B is a daucane sesquiterpene, that can be isolated from Boesenbergia longiflora rhizomes. Longiferone B shows anti-inflammatory activity against NO release with an IC50 of 21.0 μM. Longiferone B also suppresses the iNOS and COX-2 mRNA expression[1].

 Names

Name (3R,3aS,8aR)-3-Isopropenyl-6,8a-dimethyl-2,3,3a,4,8,8a-hexahydro-5(1H)-azulenone
Synonym More Synonyms

 Longiferone B Biological Activity

Description Longiferone B is a daucane sesquiterpene, that can be isolated from Boesenbergia longiflora rhizomes. Longiferone B shows anti-inflammatory activity against NO release with an IC50 of 21.0 μM. Longiferone B also suppresses the iNOS and COX-2 mRNA expression[1].
Related Catalog
Target

iNOS

COX-2

References

[1]. Sudsai T, et al. Anti-inflammatory activity of compounds from Boesenbergia longiflora rhizomes. J Ethnopharmacol. 2014 Jun 11;154(2):453-61.  

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 309.5±22.0 °C at 760 mmHg
Molecular Formula C15H22O
Molecular Weight 218.33
Flash Point 138.7±13.2 °C
Exact Mass 218.167068
LogP 4.16
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.500
Storage condition 2-8℃

 Synonyms

(3R,3aS,8aR)-3-Isopropenyl-6,8a-dimethyl-2,3,3a,4,8,8a-hexahydro-5(1H)-azulenone
5(1H)-Azulenone, 2,3,3a,4,8,8a-hexahydro-6,8a-dimethyl-3-(1-methylethenyl)-, (3R,3aS,8aR)-