Trimetazidine-N-oxide

Modify Date: 2025-09-21 19:27:13

Trimetazidine-N-oxide Structure
Trimetazidine-N-oxide structure
Common Name Trimetazidine-N-oxide
CAS Number 1644530-89-1 Molecular Weight 282.34
Density N/A Boiling Point N/A
Molecular Formula C14H22N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Trimetazidine-N-oxide


Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties.

 Names

Name Trimetazidine-N-oxide

 Trimetazidine-N-oxide Biological Activity

Description Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties.
Related Catalog
References

[1]. Sigmund G, et al. Doping control analysis of trimetazidine and characterization of major metabolites using mass spectrometric approaches. Drug Test Anal. 2014 Nov-Dec;6(11-12):1197-205.

 Chemical & Physical Properties

Molecular Formula C14H22N2O4
Molecular Weight 282.34
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