Trifluoperazine N-β-D-Glucuronide
Modify Date: 2025-08-25 16:17:51
Trifluoperazine N-β-D-Glucuronide structure
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Common Name | Trifluoperazine N-β-D-Glucuronide | ||
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| CAS Number | 165602-90-4 | Molecular Weight | 583.62000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H32F3N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Trifluoperazine N-β-D-GlucuronideTrifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1]. |
| Name | (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate |
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| Synonym | More Synonyms |
| Description | Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1]. |
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| Related Catalog | |
| In Vitro | Trifluoperazine N-Glucuronide (1~10 μg; HEK293 cells) expression levels is 0.14 unit/mg protein[1]. Trifluoperazine N-Glucuronide coexpression affects the activity of human UGT1A9. The imipramine N-glucuronide formation by the single expression system of trifluoperazine N-Glucuronide follows the Michaelis-Menten equation. Trifluoperazine N-Glucuronide interacts with the human UGT1A1 and UGT1A6, affecting the enzymatic activities[1]. |
| References |
| Molecular Formula | C27H32F3N3O6S |
|---|---|
| Molecular Weight | 583.62000 |
| Exact Mass | 583.19600 |
| PSA | 141.83000 |
| LogP | 0.97960 |
| InChIKey | AFYPHWNGUDUHIW-ARXROMJUSA-N |
| SMILES | C[N+]1(C2OC(C(=O)[O-])C(O)C(O)C2O)CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 |
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Trifluoperazine... CAS#:165602-90-4 |
| Literature: Drug Metabolism and Disposition, , vol. 40, # 5 p. 1051 - 1065 |
| Trifluoperazine N-Glucuronide |
| 1-|A-D-Glucopyranuronosyl-1-methyl-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]piperazinium Inner Salt |
| Trifluoperazine N-|A-D-GlucuronideDISCONTINUED |
| Trifluoperazine glucuronide |