Trifluoperazine N-β-D-Glucuronide
Trifluoperazine N-β-D-Glucuronide structure
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Common Name | Trifluoperazine N-β-D-Glucuronide | ||
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| CAS Number | 165602-90-4 | Molecular Weight | 583.62000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H32F3N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Trifluoperazine N-β-D-GlucuronideTrifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1]. |
Summary: Trifluoperazine N-β-D-Glucuronide, also known as (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]oxane-2-carboxylate, CAS number 165602-90-4. Molecular formula: C27H32F3N3O6S, molecular weight: 583.62000. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1]. |
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| Related Catalog | |
| In Vitro | Trifluoperazine N-Glucuronide (1~10 μg; HEK293 cells) expression levels is 0.14 unit/mg protein[1]. Trifluoperazine N-Glucuronide coexpression affects the activity of human UGT1A9. The imipramine N-glucuronide formation by the single expression system of trifluoperazine N-Glucuronide follows the Michaelis-Menten equation. Trifluoperazine N-Glucuronide interacts with the human UGT1A1 and UGT1A6, affecting the enzymatic activities[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C27H32F3N3O6S |
|---|---|
| Molecular Weight | 583.62000 |
| Exact Mass | 583.19600 |
| PSA | 141.83000 |
| LogP | 0.97960 |
| InChIKey | AFYPHWNGUDUHIW-ARXROMJUSA-N |
| SMILES | C[N+]1(C2OC(C(=O)[O-])C(O)C(O)C2O)CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Trifluoperazine... CAS#:165602-90-4 |
| Literature: Drug Metabolism and Disposition, , vol. 40, # 5 p. 1051 - 1065 |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Trifluoperazine N-Glucuronide |
| 1-|A-D-Glucopyranuronosyl-1-methyl-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]piperazinium Inner Salt |
| Trifluoperazine N-|A-D-GlucuronideDISCONTINUED |
| Trifluoperazine glucuronide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate? |
| A: Molecular weight of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate is 583.62000. |
| Q: What is the InChIKey of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate? |
| A: InChIKey of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate is AFYPHWNGUDUHIW-ARXROMJUSA-N. |
| Q: What is the SMILES notation of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate? |
| A: SMILES notation of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate is C[N+]1(C2OC(C(=O)[O-])C(O)C(O)C2O)CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1. |
| Q: What is the LogP of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate? |
| A: LogP of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate is 0.97960. |
| Q: What is the English name of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate? |
| A: The English name of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate is (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate. |
| Q: What is the Chinese name of 165602-90-4? |
| A: Chinese name of 165602-90-4 is Trifluoperazine N-Glucuronide. |
| Q: What is the CAS number of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate? |
| A: CAS number of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate is 165602-90-4. |
| Q: What are the uses of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate? |
| A: Main uses of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate: Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1]. |
| Q: What is the molecular formula of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate? |
| A: Molecular formula of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate is C27H32F3N3O6S. |
| Q: What English synonyms does (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate have? |
| A: English synonyms of (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[1-methyl-4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-ium-1-yl]oxane-2-carboxylate: Trifluoperazine N-Glucuronide, 1-|A-D-Glucopyranuronosyl-1-methyl-4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]piperazinium Inner Salt, Trifluoperazine N-|A-D-GlucuronideDISCONTINUED, Trifluoperazine glucuronide. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |