R-96544 hydrochloride

Modify Date: 2023-01-16 20:40:13

R-96544 hydrochloride structure	Common Name	R-96544 hydrochloride
	CAS Number	167144-79-8	Molecular Weight	355.47
	Density	N/A	Boiling Point	484.5ºC at 760mmHg
	Molecular Formula	C₂₂H₂₉NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	246.8ºC

Use of R-96544 hydrochloride

R-96544 (free base) is a potent, selective and competitive 5-HT2 receptor antagonist. R-96544 (free base) inhibits platelet aggregation induced by serotonin, and inhibits 5-HT2A receptor-mediated contraction of guinea pig trachea[1].

Name	(2R,4R)-4-hydroxy-2-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methylpyrrolidine

Description	R-96544 (free base) is a potent, selective and competitive 5-HT2 receptor antagonist. R-96544 (free base) inhibits platelet aggregation induced by serotonin, and inhibits 5-HT2A receptor-mediated contraction of guinea pig trachea[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Ogawa T,et al. Pharmacological profiles of R-96544, the active form of a novel 5-HT2A receptor antagonist R-102444. Eur J Pharmacol. 2002;457(2-3):107-114. doi:10.1016/s0014-2999(02)02654-7

Boiling Point	484.5ºC at 760mmHg
Molecular Formula	C₂₂H₂₉NO₃
Molecular Weight	355.47
Flash Point	246.8ºC
Exact Mass	391.19100
PSA	41.93000
LogP	4.05420
Vapour Pressure	3.35E-10mmHg at 25°C

R-96544 hydrochloride

Use of R-96544 hydrochloride

Names

R-96544 hydrochloride Biological Activity

Chemical & Physical Properties