4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-

Modify Date: 2025-08-25 20:09:53

4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)- Structure
4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)- structure
 Common Name 4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-
CAS Number 1678-14-4 Molecular Weight 308.32800
Density 1.218g/cm3 Boiling Point 528.3ºC at 760mmHg
Molecular Formula C19H16O4 Melting Point N/A
MSDS N/A Flash Point 235.1ºC

 Use of 4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-


NSC81111 is a potent and orally active EGFR-TK inhibitor with an IC50 of 0.15 nM. NSC81111 has anticaner effects[1].

 Names

Name 2,6-bis(4-methoxyphenyl)pyran-4-one
Synonym More Synonyms

 4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)- Biological Activity

Description NSC81111 is a potent and orally active EGFR-TK inhibitor with an IC50 of 0.15 nM. NSC81111 has anticaner effects[1].
Related Catalog
Target

IC50: 0.15 nM (EGFR-TK)[1]

References

[1]. Nattanan Jiwacharoenchai, et al. Discovery of potent antiproliferative agents from selected oxygen heterocycles as EGFR tyrosine kinase inhibitors from the U.S. National Cancer Institute database by in silico screening and bioactivity evaluation. Bioorg Med Chem Lett. 2022 Feb 15;58:128524.

 Chemical & Physical Properties

Density 1.218g/cm3
Boiling Point 528.3ºC at 760mmHg
Molecular Formula C19H16O4
Molecular Weight 308.32800
Flash Point 235.1ºC
Exact Mass 308.10500
PSA 48.67000
LogP 3.99100
Vapour Pressure 3.01E-11mmHg at 25°C
Index of Refraction 1.597

 Synonyms

2,6-bis-(4-methoxy-phenyl)-pyran-4-one
4H-Pyran-4-one,2,6-bis(p-methoxyphenyl)
2,6-bis(4-methoxyphenyl)-4H-pyran-4-one
2.6-Bis-<4-methoxy-phenyl>-4-pyron
2,6-Bis-(4-methoxy-phenyl)-pyran-4-on
2,6-di-(4-methoxyphenyl)-4H-pyran-4-one
2.6-Di-<4-methoxy-phenyl>-4-pyron
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Chemsrc provides 4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-(CAS#:1678-14-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)- are included as well.>> amp version: 4H-Pyran-4-one,2,6-bis(4-methoxyphenyl)-

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