9-fluorenol

Modify Date: 2024-01-02 15:21:16

9-fluorenol Structure
9-fluorenol structure
Common Name 9-fluorenol
CAS Number 1689-64-1 Molecular Weight 182.218
Density 1.3±0.1 g/cm3 Boiling Point 367.5±11.0 °C at 760 mmHg
Molecular Formula C13H10O Melting Point 153-154 °C(lit.)
MSDS Chinese USA Flash Point 131.3±11.5 °C

 Use of 9-fluorenol


9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 µM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo[1].

 Names

Name fluoren-9-ol
Synonym More Synonyms

 9-fluorenol Biological Activity

Description 9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 µM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo[1].
Related Catalog
In Vivo 1.19Pharmacokinetic parameters of 9-Fluorenol (100 mg/kg; i.p.) in rats[1] Plasma Brain Cmax , ng/g 263 4384 tmax , h 2 0.8 AUC0-t , ng h/g 1081 11639

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 367.5±11.0 °C at 760 mmHg
Melting Point 153-154 °C(lit.)
Molecular Formula C13H10O
Molecular Weight 182.218
Flash Point 131.3±11.5 °C
Exact Mass 182.073166
PSA 20.23000
LogP 2.51
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.687
Storage condition 2~8°C
Stability Stable. Combustible. Incompatible with strong oxidizing agents.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2906299090

 Synthetic Route

 Customs

HS Code 2906299090
Summary 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles7

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Assessing hazardous risks of indoor airborne polycyclic aromatic hydrocarbons in the kitchen and its association with lung functions and urinary PAH metabolites in kitchen workers.

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 Synonyms

9-Hydroxy fluorene
fluorenol
9H-Fluoren-9-ol
fluoren-9-ol
9-Fluorenol
MFCD00001135
EINECS 216-879-0
9-Hydroxyfluorene
9H-Fluorene-9-ol
fluorene, 9-hydroxy-
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