I-191

Modify Date: 2025-08-25 08:15:52

I-191 Structure
I-191 structure
Common Name I-191
CAS Number 1690172-25-8 Molecular Weight 423.48
Density N/A Boiling Point N/A
Molecular Formula C23H26FN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of I-191


I-191 is a protease-activated receptor 2 (PAR-2) signaling pathway inhibitor extracted from patent WO2015048245A1. I-191 inhibits PAR-2 activators such as SLIGKV, Trypsin, and Thrombin with IC50s of 0.0014 μM, 0.0023 μM, 0.32 μM, respectively[1].

 Names

Name I-191

 I-191 Biological Activity

Description I-191 is a protease-activated receptor 2 (PAR-2) signaling pathway inhibitor extracted from patent WO2015048245A1. I-191 inhibits PAR-2 activators such as SLIGKV, Trypsin, and Thrombin with IC50s of 0.0014 μM, 0.0023 μM, 0.32 μM, respectively[1].
Related Catalog
Target

IC50: 0.0014 μM (SLIGKV), 0.0023 μM (Trypsin), 0.32 μM (Thrombin)[1]

References

[1]. Luc J. Farmer, et al. Imidazopyridazines useful as inhibitors of the par-2 signaling pathway. WO2015048245A1.

 Chemical & Physical Properties

Molecular Formula C23H26FN5O2
Molecular Weight 423.48
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