11-Keto-beta-boswellic acid

Modify Date: 2026-07-01 18:16:47

11-Keto-beta-boswellic acid Structure
11-Keto-beta-boswellic acid structure
Common Name 11-Keto-beta-boswellic acid
CAS Number 17019-92-0 Molecular Weight 470.68400
Density 1.14g/cm3 Boiling Point 591.8ºC at 760mmHg
Molecular Formula C30H46O4 Melting Point N/A
MSDS Chinese USA Flash Point 325.8ºC

 Use of 11-Keto-beta-boswellic acid


11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production[1].

 Names

Name 11-Keto β-Boswellic Acid
Synonym More Synonyms

 11-Keto-beta-boswellic acid Biological Activity

Description 11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production[1].
Related Catalog
Target

NF-κB

References

[1]. Miscioscia E, et al. Measurement of 3-acetyl-11-keto-beta-boswellic acid and 11-keto-beta-boswellic acid in Boswellia serrata Supplements Administered to Dogs. BMC Vet Res. 2019 Aug 1;15(1):270.

 Chemical & Physical Properties

Density 1.14g/cm3
Boiling Point 591.8ºC at 760mmHg
Molecular Formula C30H46O4
Molecular Weight 470.68400
Flash Point 325.8ºC
Exact Mass 470.34000
PSA 74.60000
LogP 6.26850
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.561
InChIKey YIMHGPSYDOGBPI-UHFFFAOYSA-N
SMILES CC1CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(O)C(C)(C(=O)O)C5CCC43C)C2C1C
Storage condition 2-8C

 Safety Information

RIDADR NONH for all modes of transport
HS Code 29189900

 Synthetic Route

~%

11-Keto-beta-boswellic acid Structure

11-Keto-beta-bo...

CAS#:17019-92-0

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Literature: WO2006/95355 A1, ; Page/Page column 12 ;

 Precursor & DownStream

Precursor  1

DownStream  1

 11-Keto-beta-boswellic acidBioassay

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Name: Anti-inflammatory activity in BALB/c mouse assessed as inhibition of LPS-induced IL-6...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3756641
Name: Inhibition of lipoxygenase 5 product formation from endogenous substrate in Calcium a...
Source: ChEMBL
Target: Polyunsaturated fatty acid 5-lipoxygenase
External Id: CHEMBL974648
Name: Anti-inflammatory activity in BALB/c mouse assessed as inhibition of LPS-induced TNFa...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL3756640
Name: Cytotoxicity against human FR2 cells assessed as cell viability at 10 uM after 48 hrs...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3756455
Name: Anti-inflammatory activity in human PBMC assessed as inhibition of LPS-induced IL-6 e...
Source: ChEMBL
Target: PBMC
External Id: CHEMBL3756454
Name: Anti-inflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalp...
Source: ChEMBL
Target: PBMC
External Id: CHEMBL3756453
Name: Cytotoxicity against human MCF7 cells at 10 uM after 48 hrs
Source: ChEMBL
Target: MCF7
External Id: CHEMBL901506
Name: Cytotoxicity against human DU145 cells at 10 uM after 48 hrs
Source: ChEMBL
Target: DU-145
External Id: CHEMBL901507
Name: Cytotoxicity against human SW620 cells at 10 uM after 48 hrs
Source: ChEMBL
Target: SW-620
External Id: CHEMBL901508
Name: Inhibition of PTP1B (unknown origin)
Source: ChEMBL
Target: Tyrosine-protein phosphatase non-receptor type 1
External Id: CHEMBL3055898
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 Synonyms

11-keto-beta-Boswellic acid
(3α,5ξ,9ξ,18ξ)-3-Hydroxy-11-oxours-12-en-24-oic acid
11-KETO-β-BOSWELLIC ACID
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