Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl-

Modify Date: 2024-01-12 11:12:56

Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl- Structure
Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl- structure
Common Name Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl-
CAS Number 17127-48-9 Molecular Weight 297.34800
Density 1.33g/cm3 Boiling Point 470.8ºC at 760mmHg
Molecular Formula C18H19NO3 Melting Point N/A
MSDS N/A Flash Point 238.5ºC

 Use of Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl-


Glaziovine, a proaporphine alkaloid, has anxiolytic activity. Glaziovine can be used for neuropharmacological research[1].

 Names

Name Glaziovine
Synonym More Synonyms

  Biological Activity

Description Glaziovine, a proaporphine alkaloid, has anxiolytic activity. Glaziovine can be used for neuropharmacological research[1].
Related Catalog
References

[1]. F.D. Bellamy, et al. Synthesis of derivatives structurally related to glaziovine. Tetrahedron. Volume 39, Issue 17, 1983, Pages 2803-2806.

 Chemical & Physical Properties

Density 1.33g/cm3
Boiling Point 470.8ºC at 760mmHg
Molecular Formula C18H19NO3
Molecular Weight 297.34800
Flash Point 238.5ºC
Exact Mass 297.13600
PSA 49.77000
LogP 2.20430
Vapour Pressure 1.74E-09mmHg at 25°C
Index of Refraction 1.668

 Synthetic Route

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Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl- Structure

Spiro[2,5-cyclo...

CAS#:17127-48-9

Detail
Literature: Canonica, Luigi; Nali, Micaela; Rindone, Bruno; Tollari, Stefano; Marchesini, Augusto Gazzetta Chimica Italiana, 1985 , vol. 115, # 1 p. 1 - 6

~%

Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl- Structure

Spiro[2,5-cyclo...

CAS#:17127-48-9

Detail
Literature: Canonica, Luigi; Nali, Micaela; Rindone, Bruno; Tollari, Stefano; Marchesini, Augusto Gazzetta Chimica Italiana, 1985 , vol. 115, # 1 p. 1 - 6

~%

Spiro[2,5-cyclohexadiene-1,7'(1'H)-cyclopent[ij]isoquinolin]-4-one,2',3',8',8'a-tetrahydro-6'-hydroxy-5'-methoxy-1'-methyl- Structure

Spiro[2,5-cyclo...

CAS#:17127-48-9

Detail
Literature: Canonica, Luigi; Nali, Micaela; Rindone, Bruno; Tollari, Stefano; Marchesini, Augusto Gazzetta Chimica Italiana, 1985 , vol. 115, # 1 p. 1 - 6

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

Unii-ke7J8A65p6
Glaziovina [inn-spanish]
N-Methyl-crotsparin
(+-)-Glaziovin
Glaziovinum
Glaziovina
Glaziovinum [inn-latin]
N-methylcrotsparine