4-Hydroxybenzyl alcohol

Modify Date: 2025-08-22 11:06:25

4-Hydroxybenzyl alcohol Structure
4-Hydroxybenzyl alcohol structure
 Common Name 4-Hydroxybenzyl alcohol
CAS Number 623-05-2 Molecular Weight 124.137
Density 1.2±0.1 g/cm3 Boiling Point 252.0±0.0 °C at 760 mmHg
Molecular Formula C7H8O2 Melting Point 114-122 °C(lit.)
MSDS Chinese USA Flash Point 145.8±15.0 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of 4-Hydroxybenzyl alcohol


4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4].

 Names

Name p-hydroxybenzyl alcohol
Synonym More Synonyms

 4-Hydroxybenzyl alcohol Biological Activity

Description 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4].
Related Catalog
In Vitro 4-Hydroxybenzyl alcohol inhibits proliferation of eEND2 cells and suppresses the migration of eEND2 cells, accompanied by inhibition of actin filament reorganization[2]. 4-Hydroxybenzyl alcohol induces apoptotic death of tumor cells[3].
In Vivo 4-Hydroxybenzyl alcohol possesses antiangiogenic, anti-inflammatory and anti-nociceptive activity possibly via its down-regulating activity on NO production[1]. 4-Hydroxybenzyl alcohol (200 mg/kg) efficiently inhibits growth and angiogenesis of developing tumors[3]. 4-Hydroxybenzyl alcohol ameliorates ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect may be partly related to attenuate apoptosis pathway[4].
References

[1]. Lim EJ, et al. Anti-angiogenic, anti-inflammatory and anti-nociceptive activity of 4-hydroxybenzyl alcohol. J Pharm Pharmacol. 2007 Sep;59(9):1235-40.

[2]. Laschke MW, et al. In vitro and in vivo evaluation of the anti-angiogenic actions of 4-hydroxybenzyl alcohol. Br J Pharmacol. 2011 Jun;163(4):835-44.

[3]. Laschke MW, et al. 4-hydroxybenzyl alcohol: a novel inhibitor of tumor angiogenesis and growth. Life Sci. 2013 Jul 19;93(1):44-50.

[4]. Yu SS, et al. Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats. Brain Res. 2010 Jan 13;1308:167-75.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 252.0±0.0 °C at 760 mmHg
Melting Point 114-122 °C(lit.)
Molecular Formula C7H8O2
Molecular Weight 124.137
Flash Point 145.8±15.0 °C
Exact Mass 124.052429
PSA 40.46000
LogP 0.30
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.596
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DA4796800
HS Code 29072900

 Synthetic Route

 Customs

HS Code 2907299090
Summary 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

 Articles31

More Articles
Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins

Bioorg. Med. Chem. 17 , 896-904, (2009)

This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoret...

High tolerance and physiological mechanism of Zymomonas mobilis to phenolic inhibitors in ethanol fermentation of corncob residue.

Biotechnol. Bioeng. 112 , 1770-82, (2015)

Corncob residue as the lignocellulosic biomass accumulated phenolic compounds generated from xylitol production industry. For utilization of this biomass, Zymomonas mobilis ZM4 was tested as the ethan...

Predicting the substrate specificity of a glycosyltransferase implicated in the production of phenolic volatiles in tomato fruit.

FEBS J. 278(2) , 390-400, (2011)

The volatile compounds that constitute the fruit aroma of ripe tomato (Solanum lycopersicum) are often sequestered in glycosylated form. A homology-based screen was used to identify the gene SlUGT5, w...

 Synonyms

4-(Hydroxymethyl)benzolol
(4-Hydroxyphenyl)methanol
Gastrodigenin
p-Methylolphenol
4-hydroxymethyl-phenol
PARA-ALCOHOLPHENOL
4-Hydroxybenzyl alcohol
4-hydroxybenzyl-alcohol
Benzyl alcohol, p-hydroxy- (8CI)
p-(Hydroxymethyl)phenol
p-Hydroxybenzyl
4-(Hydroxymethyl)phenol
RARECHEM AL BD 0098
EINECS 210-768-0
Benzenemethanol, 4-hydroxy-
Benzyl alcohol, p-hydroxy-
4-METHYLOLPHENOL
benzyl alcohol, 4-hydroxy-
P-HYDROXYBENZYL ALCOHOL
MFCD00004658
4-HYDROXY-BENZYL-ALCOHOL
α-Hydroxy-p-cresol
FEMA 3987
Bisoprolol Impurity 19
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

4-Hydroxybenzyl alcohol suppliers

Price: ￥99.4/25g

Reference only. check more 4-Hydroxybenzyl alcohol price

Related Compounds: More...
3-Bromo-4-hydroxybenzyl alcohol
29922-56-3
3-Amino-4-hydroxybenzyl alcohol
52820-13-0
2-methyl-4-hydroxybenzyl alcohol
10482-16-3
3-Ethoxy-4-hydroxybenzyl alcohol
4912-58-7
2-fluoro-4-hydroxybenzyl alcohol
96740-92-0
3-fluoro-4-hydroxybenzyl alcohol
96740-93-1
2-methyl-4-hydroxybenzyl alcohol
22574-58-9
3-allyloxy-4-hydroxybenzyl alcohol
756525-88-9
3,5-DIBROMO-4-HYDROXYBENZYL ALCOHOL
2316-62-3
4-Bromo-5-ethyl-2-(4-fluorophenyl)-6-methylpyrimidine
2444576-15-0
4-Bromo-5-ethyl-6-methyl-2-(3-methylthiophen-2-yl)pyrimidine
2444046-83-5
4-Bromo-5-ethyl-6-methyl-2-(1-phenylethyl)pyrimidine
2448415-25-4
2-(2-Chloro-3-methoxyphenyl)pyrimidin-4-amine
2448415-34-5
1-methyl-N-(pyridin-2-yl)-1H-pyrazole-4-carbohydrazide
2167027-31-6
2-(4-Methyl-2-oxo-1-piperidinyl)benzaldehyde
262861-00-7
Spiro[naphthalene-2(1H),2a(2)-[1,3,6]trioxocin]
13393-96-9
1-[3-(Methoxymethyl)furan-2-yl]prop-2-en-1-ol
2228171-66-0
Tricyclo[3.2.1.02,4]oct-6-ene, 2,4-diphenyl-
28021-00-3
1-[3-bromo-5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)benzoyl]pyrrolidine-3-carboxylic acid
2172182-45-3
Chemsrc provides 4-Hydroxybenzyl alcohol(CAS#:623-05-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 4-Hydroxybenzyl alcohol are included as well.>> amp version: 4-Hydroxybenzyl alcohol

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved