α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Modify Date: 2025-10-29 17:21:58

α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Structure
α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) structure
Common Name α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
CAS Number 171869-93-5 Molecular Weight 1778.907
Density N/A Boiling Point N/A
Molecular Formula C79H110F3N21O21S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)


α-Melanocyte-Stimulating Hormone (MSH), amide TFA is an endogenous neuropeptide, with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC), acts as an endogenous melanocortin receptor 4 (MC4R) agonist[1][2].

 Names

Name α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
Synonym More Synonyms

  Biological Activity

Description α-Melanocyte-Stimulating Hormone (MSH), amide TFA is an endogenous neuropeptide, with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC), acts as an endogenous melanocortin receptor 4 (MC4R) agonist[1][2].
Related Catalog
Target

MC4R[2]

References

[1]. Madhuri Singh, et al. C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus. Antimicrob Agents Chemother. 2011 May;55(5):1920-9.

 Chemical & Physical Properties

Molecular Formula C79H110F3N21O21S
Molecular Weight 1778.907
Exact Mass 1777.785767
InChIKey FEOXCJFWEWYJIH-UHFFFAOYSA-N
SMILES CSCCC(NC(=O)C(CO)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(C)=O)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(C(N)=O)C(C)C.O=C(O)C(F)(F)F

 Synonyms

N-Acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide trifluoroacetate (1:1)
L-Valinamide, N-acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-, compd. with 2,2,2-trifluoroacetic acid (1:1)
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