IR820

Modify Date: 2024-01-01 19:15:56

IR820 Structure
IR820 structure
Common Name IR820
CAS Number 172616-80-7 Molecular Weight 849.47200
Density N/A Boiling Point N/A
Molecular Formula C46H50ClN2NaO6S2 Melting Point >300ºC
MSDS Chinese USA Flash Point N/A

 Use of IR820


IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals[1].

 Names

Name New Indocyanine Green
Synonym More Synonyms

 IR820 Biological Activity

Description IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals[1].
Related Catalog
In Vitro Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 体内[1]: 1. 将粉末状的 IR-820 与磷酸盐缓冲液 (PBS) 新鲜混合至终浓度为 0.2 mM,取 100 μL 此溶液注射到实验动物中。 2.使用 2 组四只无毛 SKHi/sKHl 小鼠。 第一组通过静脉尾静脉注射 IR-820,而第二组通过腹膜内注射。 3. IR-820 的最大激发和发射波长分别为 710 nm 和 820 nm。 两组连续成像 8 天。
References

[1]. Suresh I Prajapati, et al. Near-infrared imaging of injured tissue in living subjects using IR-820. Mol Imaging. 2009 Jan-Feb;8(1):45-54.  

 Chemical & Physical Properties

Melting Point >300ºC
Molecular Formula C46H50ClN2NaO6S2
Molecular Weight 849.47200
Exact Mass 848.27000
PSA 137.41000
LogP 12.04650

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

IR-820,2-[2-[2-Chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benzo[e]indolium hydroxide inne
2-(2-(2-Chloro-3-((1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene)ethylidene)-1-cyclohexen-1-yl]
New indocyanine Green
IR-820
2-[2-[2-Chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benzo(e)indolium hydroxide,inner salt
2-[2-[2-chloro-3-[[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2h-benzo[e]indol-2-ylidene]-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,1-dimethyl-3-(4-sulfobutyl)-1h-benzo[e]indolium hydroxide inner salt,sodium salt
MFCD04038859
IR820
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