4-(2-thienyl)pyrimidine-2-thiol

Modify Date: 2026-08-31 12:59:56

4-(2-thienyl)pyrimidine-2-thiol Structure
4-(2-thienyl)pyrimidine-2-thiol structure
Common Name 4-(2-thienyl)pyrimidine-2-thiol
CAS Number 175202-75-2 Molecular Weight 194.27700
Density 1.41g/cm3 Boiling Point 344.4ºC at 760 mmHg
Molecular Formula C8H6N2S2 Melting Point 206ºC
MSDS N/A Flash Point 162.1ºC

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 6-thiophen-2-yl-1H-pyrimidine-2-thione
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.41g/cm3
Boiling Point 344.4ºC at 760 mmHg
Melting Point 206ºC
Molecular Formula C8H6N2S2
Molecular Weight 194.27700
Flash Point 162.1ºC
Exact Mass 193.99700
PSA 92.82000
LogP 2.49380
Vapour Pressure 6.6E-05mmHg at 25°C
Index of Refraction 1.746
InChIKey IPUPBWKUWAKTQL-UHFFFAOYSA-N
SMILES S=c1nccc(-c2cccs2)[nH]1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 4-(2-Thienyl)pyrimidine-2-thiol 97% Material Safety Data Sheet
Synonym:
CAS: 175202-75-2
Section 1 - Chemical Product MSDS Name:4-(2-Thienyl)pyrimidine-2-thiol 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
175202-75-2 4-(2-Thienyl)pyrimidine-2-thiol 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 175202-75-2: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 206 - 215 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C8H6N2S2
Molecular Weight: 194

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, ammonia.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 175202-75-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
4-(2-Thienyl)pyrimidine-2-thiol - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 175202-75-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 175202-75-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 175202-75-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xn
Risk Phrases R20/21/22
Safety Phrases S26
HS Code 2934999090

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 4-(2-thienyl)pyrimidine-2-thiolBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

4-(2-THIENYL)PYRIMIDINE-2-THIOL
4-thiophen-2-ylpyrimidine-2-thiol

 4-(2-thienyl)pyrimidine-2-thiol | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: Polar surface area (PSA) of 6-thiophen-2-yl-1H-pyrimidine-2-thione is 92.82000.
Q: What is the SMILES notation of 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: SMILES notation of 6-thiophen-2-yl-1H-pyrimidine-2-thione is S=c1nccc(-c2cccs2)[nH]1.
Q: What is the InChIKey of 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: InChIKey of 6-thiophen-2-yl-1H-pyrimidine-2-thione is IPUPBWKUWAKTQL-UHFFFAOYSA-N.
Q: What is the molecular formula of 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: Molecular formula of 6-thiophen-2-yl-1H-pyrimidine-2-thione is C8H6N2S2.
Q: What English synonyms does 6-thiophen-2-yl-1H-pyrimidine-2-thione have?
A: English synonyms of 6-thiophen-2-yl-1H-pyrimidine-2-thione: 4-(2-THIENYL)PYRIMIDINE-2-THIOL, 4-thiophen-2-ylpyrimidine-2-thiol.
Q: What is the safety information for 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: Safety information for 6-thiophen-2-yl-1H-pyrimidine-2-thione: S26.
Q: What is the English name of 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: The English name of 6-thiophen-2-yl-1H-pyrimidine-2-thione is 6-thiophen-2-yl-1H-pyrimidine-2-thione.
Q: What is the melting point of 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: Melting point of 6-thiophen-2-yl-1H-pyrimidine-2-thione is 206ºC.
Q: What is the molecular weight of 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: Molecular weight of 6-thiophen-2-yl-1H-pyrimidine-2-thione is 194.27700.
Q: What is the CAS number of 6-thiophen-2-yl-1H-pyrimidine-2-thione?
A: CAS number of 6-thiophen-2-yl-1H-pyrimidine-2-thione is 175202-75-2.

 4-(2-thienyl)pyrimidine-2-thiolfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

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