4-Methylumbelliferyl butyrate

Modify Date: 2024-01-06 00:11:06

4-Methylumbelliferyl butyrate Structure
4-Methylumbelliferyl butyrate structure
Common Name 4-Methylumbelliferyl butyrate
CAS Number 17695-46-4 Molecular Weight 246.25900
Density 1.197 g/cm3 Boiling Point 393.4ºC at 760 mmHg
Molecular Formula C14H14O4 Melting Point 90-92ºC(lit.)
MSDS Chinese USA Flash Point 199.8ºC

 Use of 4-Methylumbelliferyl butyrate


4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187)[1].

 Names

Name 4-Methylumbelliferyl butyrate
Synonym More Synonyms

 4-Methylumbelliferyl butyrate Biological Activity

Description 4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187)[1].
Related Catalog
References

[1]. Uisung Lee, et al. Selective Butyrate Esterase Probe for the Rapid Colorimetric and Fluorogenic Identification of Moraxella catarrhalis. Anal Chem. 2020 Dec 15;92(24):16051-16057.  

 Chemical & Physical Properties

Density 1.197 g/cm3
Boiling Point 393.4ºC at 760 mmHg
Melting Point 90-92ºC(lit.)
Molecular Formula C14H14O4
Molecular Weight 246.25900
Flash Point 199.8ºC
Exact Mass 246.08900
PSA 56.51000
LogP 2.80690
Vapour Pressure 2.13E-06mmHg at 25°C
Index of Refraction 1.545
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+
Risk Phrases R26/27/28
Safety Phrases 24/25
RIDADR NONH for all modes of transport
HS Code 2932209090

 Synthetic Route

~94%

4-Methylumbelliferyl butyrate Structure

4-Methylumbelli...

CAS#:17695-46-4

Literature: Instytut Chemii Organicznej, Polska Akademia Nauk Patent: WO2009/67031 A1, 2009 ; Location in patent: Page/Page column 14 ;

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4-Methylumbelliferyl butyrate Structure

4-Methylumbelli...

CAS#:17695-46-4

Literature: Journal of the American Chemical Society, , vol. 62, p. 1441,1443

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles7

More Articles
Rapid identification of Branhamella catarrhalis with 4-methylumbelliferyl butyrate.

J. Clin. Microbiol. 26 , 1227, (1988)

Branhamella catarrhalis can be distinguished from Neisseria spp. by the presence of butyrate esterase. This enzyme can be rapidly detected when 4-methylumbelliferyl butyrate is used as the substrate. ...

Characterization of an acidic cold-adapted cutinase from Thielavia terrestris and its application in flavor ester synthesis.

Food Chem. 188 , 439-45, (2015)

An acidic cutinase (TtcutB) from Thielavia terrestris CAU709 was purified to apparent homogeneity with 983 Um g(-1) specific activity. The molecular mass of the enzyme was estimated to be 27.3 and 27....

Fluorescence spectroscopic analysis of the structure and dynamics of Bacillus subtilis lipase A governing its activity profile under alkaline conditions.

Eur. Biophys. J. 44 , 655-65, (2015)

Because of their vast diversity of substrate specificity and reaction conditions, lipases are versatile materials for biocatalysis. Lipase A from Bacillus subtilis (BSLA) is the smallest lipase yet di...

 Synonyms

(4-methyl-2-oxochromen-7-yl) butanoate
MFCD00038087
EINECS 241-694-7