Nociceptin (1-13) amide trifluoroacetate salt

Modify Date: 2024-01-02 19:04:04

Nociceptin (1-13) amide trifluoroacetate salt Structure
Nociceptin (1-13) amide trifluoroacetate salt structure
 Common Name Nociceptin (1-13) amide trifluoroacetate salt
CAS Number 178064-02-3 Molecular Weight 1381.59
Density N/A Boiling Point N/A
Molecular Formula C61H100N22O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nociceptin (1-13) amide trifluoroacetate salt


Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes[1][2].

 Names

Name Nociceptin (1-13)NH2
Synonym More Synonyms

  Biological Activity

Description Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes[1][2].
Related Catalog
Target

Ki: 0.75 nM (binding to rat forebrain membranes)[1] pEC50: 7.9 (in mouse vas deferens)[2]

References

[1]. Varani K, et al. Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships. Br J Pharmacol. 1998 Dec;125(7):1485-90.

[2]. Calo' G, et al. Pharmacology of nociceptin and its receptor: a novel therapeutic target. Br J Pharmacol. 2000 Apr;129(7):1261-83.

 Chemical & Physical Properties

Molecular Formula C61H100N22O15
Molecular Weight 1381.59
Exact Mass 1380.77000
PSA 634.61000
LogP 1.06750

 Synonyms

phe-gly-gly-phe-thr-gly-ala-arg-lys-ser-ala-arg-lys-nh2
h-phe-gly-gly-phe-thr-gly-ala-arg-lys-ser-ala-arg-lys-nh2
phe-gly-gly-phe-thr-gly-ala-arg-lys-nh2
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Chemsrc provides CAS#:178064-02-3 MSDS, density, melting point, boiling point, structure, etc. Its name is Nociceptin (1-13) amide trifluoroacetate salt>> amp version: Nociceptin (1-13) amide trifluoroacetate salt

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