NGD 94-1

Modify Date: 2024-01-06 19:11:14

NGD 94-1 Structure
NGD 94-1 structure
Common Name NGD 94-1
CAS Number 178928-68-2 Molecular Weight 320.39
Density 1.259g/cm3 Boiling Point 578.2ºC at 760mmHg
Molecular Formula C18H20N6 Melting Point N/A
MSDS N/A Flash Point 303.5ºC

 Use of NGD 94-1


NGD94-1 is a specific dopamine D4 receptor antagonist. NGD94-1 can effectively reverse Phencyclidine-induced cognitive impairment in marmosets. NGD94-1 can be used in the study of psychiatric diseases[1].

 Names

Name 2-{4-[(2-Phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl}pyrimidine

 NGD 94-1 Biological Activity

Description NGD94-1 is a specific dopamine D4 receptor antagonist. NGD94-1 can effectively reverse Phencyclidine-induced cognitive impairment in marmosets. NGD94-1 can be used in the study of psychiatric diseases[1].
Related Catalog
References

[1]. Jentsch JD, et al. Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys. Psychopharmacology (Berl). 1999 Feb;142(1):78-84.  

 Chemical & Physical Properties

Density 1.259g/cm3
Boiling Point 578.2ºC at 760mmHg
Molecular Formula C18H20N6
Molecular Weight 320.39
Flash Point 303.5ºC
Exact Mass 320.17500
PSA 60.94000
LogP 2.19180
Vapour Pressure 2.3E-13mmHg at 25°C
Index of Refraction 1.647
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