DMEA-PNU-159682

Modify Date: 2024-01-03 22:55:17

DMEA-PNU-159682 Structure
DMEA-PNU-159682 structure
Common Name DMEA-PNU-159682
CAS Number 1799421-48-9 Molecular Weight 755.76
Density N/A Boiling Point N/A
Molecular Formula C37H45N3O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DMEA-PNU-159682


DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].

 Names

Name DMEA-PNU-159682

 DMEA-PNU-159682 Biological Activity

Description DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].
Related Catalog
Target

Daunorubicins/Doxorubicins

References

[1]. Chen Jingkang, et al. Disubstituted maleic amide class connexon for antibody-drug conjugate and its preparation method and application. CN108101825A.

[2]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

 Chemical & Physical Properties

Molecular Formula C37H45N3O14
Molecular Weight 755.76