Milvexian

Modify Date: 2025-08-27 17:22:43

Milvexian Structure
Milvexian structure
Common Name Milvexian
CAS Number 1802425-99-5 Molecular Weight 626.44
Density 1.60±0.1 g/cm3 Boiling Point N/A
Molecular Formula C28H23Cl2F2N9O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Milvexian


Milvexian (BMS-986177), an effective antithrombotic agent, is an orally-bioavailable, reversible and direct inhibitor of human and rabbit factor XIa (FXIa) with Ki of 0.11, and 0.38 nM, respectively[1].

 Names

Name Milvexian
Synonym More Synonyms

 Milvexian Biological Activity

Description Milvexian (BMS-986177), an effective antithrombotic agent, is an orally-bioavailable, reversible and direct inhibitor of human and rabbit factor XIa (FXIa) with Ki of 0.11, and 0.38 nM, respectively[1].
Related Catalog
References

[1]. Wong P, et al. Small-Molecule Factor XIa Inhibitor, BMS-986177/JNJ-70033093, Prevents and Treats Arterial Thrombosis in Rabbits at Doses that Preserve Hemostasis [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1).

 Chemical & Physical Properties

Density 1.60±0.1 g/cm3
Molecular Formula C28H23Cl2F2N9O2
Molecular Weight 626.44
InChIKey FSWFYCYPTDLKON-CMJOXMDJSA-N
SMILES CC1CCCC(n2cnc(-c3cc(Cl)ccc3-n3cc(Cl)nn3)cc2=O)c2cc(ccn2)-c2c(cnn2C(F)F)NC1=O
Storage condition 2-8°C

 Synonyms

BMS-986177
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