Ravulizumab

Modify Date: 2024-04-12 19:03:40

Ravulizumab Structure
Ravulizumab structure
Common Name Ravulizumab
CAS Number 1803171-55-2 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ravulizumab


Ravulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis[1].

 Names

Name Ravulizumab

 Ravulizumab Biological Activity

Description Ravulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis[1].
Related Catalog
Target

complement protein C5[1]

In Vitro Ravulizumab 与 C5 高亲和力结合并抑制 C5a 和 C5b 的形成,从而防止免疫激活和溶血[1]。
References

[1]. Lee JW, et, al. Ravulizumab (ALXN1210) vs eculizumab in adult patients with PNH naive to complement inhibitors: the 301 study. Blood. 2019 Feb 7;133(6):530-539.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties