Hydroxyzine-d8 (hydrochloride)

Modify Date: 2025-09-12 18:15:54

Hydroxyzine-d8 (hydrochloride) Structure
Hydroxyzine-d8 (hydrochloride) structure
Common Name Hydroxyzine-d8 (hydrochloride)
CAS Number 1808202-93-8 Molecular Weight 455.875
Density N/A Boiling Point N/A
Molecular Formula C21H21D8Cl3N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxyzine-d8 (hydrochloride)


Hydroxyzine-d8 Dihydrochloride is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

 Names

Name Hydroxyzine-d8 (hydrochloride)
Synonym More Synonyms

 Hydroxyzine-d8 (hydrochloride) Biological Activity

Description Hydroxyzine-d8 Dihydrochloride is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63.

[3]. Morichi, R. and G. Pepeu, A study of the influence of hydroxyzine and diazepam on morphine antinociceptoion in the rat. Pain, 1979. 7(2): p. 173-80.

[4]. Nikita Shekhar Sawantdesai, et al. Evaluation of anxiolytic effects of aripiprazole and hydroxyzine as a combination in mice. J Basic Clin Pharm. 2016 Sep;7(4):97-104.

 Chemical & Physical Properties

Molecular Formula C21H21D8Cl3N2O2
Molecular Weight 455.875
Exact Mass 454.179688

 Synonyms

Hydroxyzine-d8 (hydrochloride)
Ethanol, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl-2,2,3,3,5,5,6,6-d8]ethoxy]-, hydrochloride (1:2)
2-(2-{4-[(4-Chlorophenyl)(phenyl)methyl](2H8)-1-piperazinyl}ethoxy)ethanol dihydrochloride
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Hydroxyzine-d8 (hydrochloride) suppliers

Hydroxyzine-d8 (hydrochloride) price

Related Compounds: More...
Hydroxyzine D8
1189480-47-4
hydroxyzine hydrochloride
163837-38-5
hydroxyzine hydrochloride
163837-37-4
Levofloxacin-d8 hydrochloride
2699607-50-4
Bendamustine-d8 hydrochloride
1185068-23-8
Morpholine-d8 hydrochloride
1107650-56-5
Ciprofloxacin-D8 hydrochloride hydrate (see Data Sheet)
1216659-54-9
Sarafloxacin-d8 hydrochloride
1352879-52-7
Loxapine-d8 hydrochloride
1246820-19-8
2-(4-Fluorophenyl)-4-(4-(4-fluorophenyl)piperazin-1-yl)pyrazolo[1,5-a]pyrazine
1111319-79-9
4-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazine
1115318-23-4
1-[(2-Methoxy-4,5-dimethylphenyl)sulfonyl]-2-methylpiperidine
1206129-71-6
5-(4-fluorophenyl)-1-((3-(p-tolyl)-1,2,4-oxadiazol-5-yl)methyl)-1,6a-dihydropyrrolo[3,4-d][1,2,3]triazole-4,6(3aH,5H)-dione
1207006-75-4
1-{[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-5-(4-fluorophenyl)-1H,3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2,3]triazole-4,6-dione
1207031-54-6
1-{[3-(4-bromophenyl)-1,2,4-oxadiazol-5-yl]methyl}-5-(4-fluorophenyl)-1H,3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2,3]triazole-4,6-dione
1207031-51-3
1-((3-(2-bromophenyl)-1,2,4-oxadiazol-5-yl)methyl)-5-(4-fluorophenyl)-1,6a-dihydropyrrolo[3,4-d][1,2,3]triazole-4,6(3aH,5H)-dione
1207031-52-4
1-{[3-(2,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-5-(4-fluorophenyl)-1H,3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2,3]triazole-4,6-dione
1207006-87-8
5-(4-fluorophenyl)-1-((3-(m-tolyl)-1,2,4-oxadiazol-5-yl)methyl)-1,6a-dihydropyrrolo[3,4-d][1,2,3]triazole-4,6(3aH,5H)-dione
1207031-55-7
5-(4-fluorophenyl)-1-({3-[4-(propan-2-yloxy)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-1H,3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2,3]triazole-4,6-dione
1207031-57-9