OR-S0
Modify Date: 2024-01-20 11:02:59
OR-S0 structure
|
Common Name | OR-S0 | ||
|---|---|---|---|---|
| CAS Number | 1809336-90-0 | Molecular Weight | 616.763 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H44N6O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of OR-S0OR-S0 is a potent, selective EZH2 inhibitor with IC50 of 11 nM, weakly inhibitor EZH1 (IC50=91 nM).OR-S0 inhibits H3K27me3 in HCT116 cells with IC50 of 24 nM, inhibited the growth of KARPAS‐422 cells in a dose‐dependent manner with GI50 of 210 nM. |
| Name | OR-S0 |
|---|
| Description | OR-S0 is a potent, selective EZH2 inhibitor with IC50 of 11 nM, weakly inhibitor EZH1 (IC50=91 nM).OR-S0 inhibits H3K27me3 in HCT116 cells with IC50 of 24 nM, inhibited the growth of KARPAS‐422 cells in a dose‐dependent manner with GI50 of 210 nM. |
|---|---|
| References | 1. Daisuke Honma, et al. Cancer Sci. 2017 Oct;108(10):2069-2078. |
| Molecular Formula | C34H44N6O5 |
|---|---|
| Molecular Weight | 616.763 |