MNKI-85
Modify Date: 2024-09-16 22:11:46
MNKI-85 structure
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Common Name | MNKI-85 | ||
|---|---|---|---|---|
| CAS Number | 1812885-57-6 | Molecular Weight | 418.487 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H23FN4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MNKI-85MNKI-85 is a potent and selective Mnk2 inhibitor with Ki of 31 nM, displays no inhibitory activities against Mnk1, CDK2A, CDK9T, and CDK4D; effectively inhibits the growth of AML cells that possess an M5 subtype with FLT3-internal tandem duplication mutation, a powerful pharmacologic tool in studying the Mnk2/eIF4E-mediated tumorigenic mechanism. |
| Name | MNKI-85 |
|---|
| Description | MNKI-85 is a potent and selective Mnk2 inhibitor with Ki of 31 nM, displays no inhibitory activities against Mnk1, CDK2A, CDK9T, and CDK4D; effectively inhibits the growth of AML cells that possess an M5 subtype with FLT3-internal tandem duplication mutation, a powerful pharmacologic tool in studying the Mnk2/eIF4E-mediated tumorigenic mechanism. |
|---|---|
| References | References 1. Teo T, et al. Mol Pharmacol. 2015 Aug;88(2):380-9. View Related Products by Target MNK |
| Molecular Formula | C20H23FN4O3S |
|---|---|
| Molecular Weight | 418.487 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: MNKI-85
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: MNKI-85
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: MNKI-85
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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