LEM-14
Modify Date: 2024-01-05 13:58:26
LEM-14 structure
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Common Name | LEM-14 | ||
|---|---|---|---|---|
| CAS Number | 1814881-70-3 | Molecular Weight | 478.567 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H26N4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LEM-14LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3. |
| Name | LEM-14 |
|---|
| Description | LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3. |
|---|---|
| References | References 1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4. View Related Products by Target Histone Methyltransferase (HMTase) |
| Molecular Formula | C25H26N4O4S |
|---|---|
| Molecular Weight | 478.567 |