GlyT1 inhibitor 46

Modify Date: 2024-01-10 19:38:07

GlyT1 inhibitor 46 Structure
GlyT1 inhibitor 46 structure
 Common Name GlyT1 inhibitor 46
CAS Number 1820934-93-7 Molecular Weight 387.43
Density N/A Boiling Point N/A
Molecular Formula C22H21N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GlyT1 inhibitor 46


GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1[1]. Antipsychotic activity[1].

 Names

Name GlyT1 Inhibitor 1

 GlyT1 inhibitor 46 Biological Activity

Description GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1[1]. Antipsychotic activity[1].
Related Catalog
Target

rGlyT1:38 nM (IC50)

In Vivo GlyT1 Inhibitor 1 (Compound 46) demonstrates in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg[1].
References

[1]. Santora VJ, et al. Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties. J Med Chem. 2018 Jul 26;61(14):6018-6033.

 Chemical & Physical Properties

Molecular Formula C22H21N5O2
Molecular Weight 387.43
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Chemsrc provides GlyT1 inhibitor 46(CAS#:1820934-93-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of GlyT1 inhibitor 46 are included as well.>> amp version: GlyT1 inhibitor 46

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