BCL6 inhibitor 8c

Modify Date: 2023-01-11 17:16:31

BCL6 inhibitor 8c Structure
BCL6 inhibitor 8c structure
Common Name BCL6 inhibitor 8c
CAS Number 2130878-25-8 Molecular Weight 417.846
Density N/A Boiling Point N/A
Molecular Formula C20H20ClN3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BCL6 inhibitor 8c


A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays; exhibits good cellular BCL6BTB/ BCoR PPI inhibitory activity in the submicromolar range (M2H IC50=0.72 uM), showed a good pharmacokinetic profile, which is acceptable for both in vitro and in vivo studies.

 Names

Name BCL6 inhibitor 8c

 BCL6 inhibitor 8c Biological Activity

Description A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays; exhibits good cellular BCL6BTB/ BCoR PPI inhibitory activity in the submicromolar range (M2H IC50=0.72 uM), showed a good pharmacokinetic profile, which is acceptable for both in vitro and in vivo studies.
References References 1. Yasui T, et al. Bioorg Med Chem. 2017 Sep 1;25(17):4876-4886. View Related Products by Target Bcl-2

 Chemical & Physical Properties

Molecular Formula C20H20ClN3O5
Molecular Weight 417.846

 Safety Information

Hazard Codes Xi
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