(R)-MLT-985

Modify Date: 2025-08-25 18:28:22

(R)-MLT-985 Structure
(R)-MLT-985 structure
Common Name (R)-MLT-985
CAS Number 1832577-07-7 Molecular Weight 448.27
Density N/A Boiling Point N/A
Molecular Formula C17H15Cl2N9O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-MLT-985


(R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor with an IC50 of 3 nM. (R)-MLT-985 has an IC50 of 20 nM for MALT1-dependent IL-2 production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells[1].

 Names

Name (R)-MLT-985

 (R)-MLT-985 Biological Activity

Description (R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor with an IC50 of 3 nM. (R)-MLT-985 has an IC50 of 20 nM for MALT1-dependent IL-2 production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells[1].
Related Catalog
References

[1]. Jean Quancard, et al. Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood. J Med Chem. 2020 Dec 10;63(23):14594-14608.

 Chemical & Physical Properties

Molecular Formula C17H15Cl2N9O2
Molecular Weight 448.27
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

(R)-MLT-985 suppliers

(R)-MLT-985 price