Boc-C1-PEG2-C4-Cl structure
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Common Name | Boc-C1-PEG2-C4-Cl | ||
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CAS Number | 1835705-53-7 | Molecular Weight | 294.81 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C14H27ClO4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Boc-C1-PEG2-C4-ClPROTAC Linker 1 is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand. |
Name | PROTAC Linker 1 |
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Description | PROTAC Linker 1 is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand. |
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Related Catalog | |
In Vitro | PROTAC technology employs small molecules that recruit target proteins for ubiquitination and removal by the proteasome. The synthesis of PROTAC compounds that mediate the degradation of c-ABL and BCR-ABL by recruiting either Cereblon or Von Hippel Lindau E3 ligases is reported. PROTAC Linker 1 is designated as 6-2-2[1]. |
References |
Molecular Formula | C14H27ClO4 |
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Molecular Weight | 294.81 |
Storage condition | 2-8℃ |