formoterol fumarate dihydrate

Modify Date: 2024-01-02 19:39:42

formoterol fumarate dihydrate Structure
formoterol fumarate dihydrate structure
Common Name formoterol fumarate dihydrate
CAS Number 183814-30-4 Molecular Weight 840.912
Density N/A Boiling Point 603.2ºC at 760 mmHg
Molecular Formula C42H56N4O14 Melting Point 116-120ºC
MSDS Chinese USA Flash Point 318.6ºC

 Names

Name Formoterol Fumarate Dihydrate
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 603.2ºC at 760 mmHg
Melting Point 116-120ºC
Molecular Formula C42H56N4O14
Molecular Weight 840.912
Flash Point 318.6ºC
Exact Mass 840.379272
PSA 274.70000
LogP 6.22940
Vapour Pressure 2.12E-15mmHg at 25°C
Storage condition Store at RT
Water Solubility DMSO: soluble20mg/mL

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR UN 2811 6.1 / PGII
HS Code 2924299090

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles3

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Permeation of Therapeutic Drugs in Different Formulations across the Airway Epithelium In Vitro.

PLoS ONE 10 , e0135690, (2015)

Pulmonary drug delivery is characterized by short onset times of the effects and an increased therapeutic ratio compared to oral drug delivery. This delivery route can be used for local as well as for...

Increased Dose of Inhaled Corticosteroid versus Add-On Long-acting β-Agonist for Step-Up Therapy in Asthma.

Ann. Am. Thorac. Soc. 12 , 798-806, (2015)

Guidelines advocate adding long-acting β-agonist (LABA) to inhaled corticosteroid as the preferred step-up therapy to increasing inhaled corticosteroid dose for patients with uncontrolled asthma on in...

Atomoxetine prevents dexamethasone-induced skeletal muscle atrophy in mice.

J. Pharmacol. Exp. Ther. 351(3) , 663-73, (2014)

Skeletal muscle atrophy remains a clinical problem in numerous pathologic conditions. β2-Adrenergic receptor agonists, such as formoterol, can induce mitochondrial biogenesis (MB) to prevent such atro...

 Synonyms

formoterol fumerate dihydrate
Formamide, N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (2E)-2-butenedioate, hydrate (2:1:2) (salt)
Formoterol hemifumarate,(±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamidehemifumarate
N-{2-Hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide (2E)-but-2-enedioate hydrate (2:1:2)
Formoterol fumarate dihydrate
Formoterol fumarate
N-{2-Hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)-2-propanyl]amino}ethyl]phenyl}formamide (2E)-2-butenedioate hydrate (2:1:2)