CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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LM5900000
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CHEMICAL NAME :
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Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-, disodium salt
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CAS REGISTRY NUMBER :
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18472-87-2
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LAST UPDATED :
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199701
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DATA ITEMS CITED :
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11
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MOLECULAR FORMULA :
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C20-H2-Br4-Cl4-O5.2Na
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MOLECULAR WEIGHT :
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829.64
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WISWESSER LINE NOTATION :
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T C666 BO EVJ DE FE IR BG CG DG EG FVO& LE MO NE &-NA- 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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310 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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75600 mg/kg/90W-C
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TOXIC EFFECTS :
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Tumorigenic - neoplastic by RTECS criteria Liver - tumors Endocrine - tumors
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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63 gm/kg
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SEX/DURATION :
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female 1-22 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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39600 mg/kg
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SEX/DURATION :
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female 6-16 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - musculoskeletal system
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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66 gm/kg
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SEX/DURATION :
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female 6-16 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
MUTATION DATA
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TYPE OF TEST :
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Mutation in mammalian somatic cells
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TEST SYSTEM :
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Human Lung
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DOSE/DURATION :
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3 mg/L
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REFERENCE :
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MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 30,239,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4129 No. of Facilities: 301 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1460 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4129 No. of Facilities: 559 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 9866 (estimated) No. of Female Employees: 3202 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9003 No. of Facilities: 636 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 8722 (estimated) No. of Female Employees: 6754 (estimated)
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