Tetrodotoxin citrate

Modify Date: 2024-02-04 11:48:25

Tetrodotoxin citrate Structure
Tetrodotoxin citrate structure
 Common Name Tetrodotoxin citrate
CAS Number 18660-81-6 Molecular Weight 511.39200
Density N/A Boiling Point 772.1ºC at 760 mmHg
Molecular Formula C17H25N3O15 Melting Point N/A
MSDS N/A Flash Point 420.7ºC

 Use of Tetrodotoxin citrate


Tetrodotoxin (TTx) is a potent, highly selective sodium channel blocker with IC50 of 33 nM for Nav1.6.

 Names

Name Tetrodotoxin citrate

 Chemical & Physical Properties

Boiling Point 772.1ºC at 760 mmHg
Molecular Formula C17H25N3O15
Molecular Weight 511.39200
Flash Point 420.7ºC
Exact Mass 511.12900
PSA 319.88000
Vapour Pressure 1.58E-27mmHg at 25°C
Storage condition Desiccate at -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XF8884500
CAS REGISTRY NUMBER :
18660-81-6
LAST UPDATED :
198611
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H17-N3-O8.xC6-H8-O7
MOLECULAR WEIGHT :
1664.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8 ng/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AFMMBW Archivos de la Facultad de Medicina de Madrid. (Madrid, Spain) V.1-40, 1961-81. Volume(issue)/page/year: 8,151,1965

 Safety Information

Hazard Codes T+
Risk Phrases 26/27/28
Safety Phrases 22-36/37/39-45
RTECS IO1450000
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