SU5204

Modify Date: 2024-01-09 08:19:15

SU5204 Structure
SU5204 structure
Common Name SU5204
CAS Number 186611-11-0 Molecular Weight 265.30700
Density N/A Boiling Point N/A
Molecular Formula C17H15NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SU5204


SU5204, a tyrosine kinase inhibitor extracted from patent US5792783A, has IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively[1].

 Names

Name (3E)-3-(2-Ethoxybenzylidene)-1,3-dihydro-2H-indol-2-one
Synonym More Synonyms

 SU5204 Biological Activity

Description SU5204, a tyrosine kinase inhibitor extracted from patent US5792783A, has IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively[1].
Related Catalog
Target

VEGFR2:4 μM (IC50)

HER2:51.5 μM (IC50)

References

[1]. Peng Cho Tang, et al. 3-heteroaryl-2-indolinone compounds for the treatment of disease. US5792783A.

 Chemical & Physical Properties

Molecular Formula C17H15NO2
Molecular Weight 265.30700
Exact Mass 265.11000
PSA 41.82000
LogP 3.66310

 Synonyms

MFCD04651331