2,3-Dibromopropionyl chloride

Modify Date: 2024-01-09 14:28:10

2,3-Dibromopropionyl chloride Structure
2,3-Dibromopropionyl chloride structure
Common Name 2,3-Dibromopropionyl chloride
CAS Number 18791-02-1 Molecular Weight 250.31600
Density 2.181 g/mL at 25 °C(lit.) Boiling Point 191-193 °C(lit.)
Molecular Formula C3H3Br2ClO Melting Point N/A
MSDS Chinese USA Flash Point 152 °F
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name 2,3-dibromopropanoyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.181 g/mL at 25 °C(lit.)
Boiling Point 191-193 °C(lit.)
Molecular Formula C3H3Br2ClO
Molecular Weight 250.31600
Flash Point 152 °F
Exact Mass 247.82400
PSA 17.07000
LogP 1.91020
Vapour Pressure 0.5mmHg at 25°C
Index of Refraction n20/D 1.542(lit.)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UG6657500
CHEMICAL NAME :
Propionyl chloride, 2,3-dibromo-
CAS REGISTRY NUMBER :
18791-02-1
BEILSTEIN REFERENCE NO. :
1749801
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C3-H3-Br2-Cl-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(4),90,1984
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1360 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(4),90,1984
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
19200 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(4),90,1984

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H314-H335
Precautionary Statements P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34;R36/37
Safety Phrases S23-S26-S27-S28-S36/37/39-S45
RIDADR UN 3265 8/PG 2
WGK Germany 3
RTECS UG6657500
Packaging Group II
Hazard Class 8
HS Code 2915900090

 Synthetic Route

~90%

2,3-Dibromopropionyl chloride Structure

2,3-Dibromoprop...

CAS#:18791-02-1

Literature: Tomashevskii, A. A.; Sokolov, V. V.; Potekhin, A. A. Russian Journal of Organic Chemistry, 1994 , vol. 30, # 10 p. 1610 - 1618 Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 10 p. 1528 - 1536

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2,3-Dibromopropionyl chloride Structure

2,3-Dibromoprop...

CAS#:18791-02-1

Literature: Annales de Chimie (Cachan, France), , vol. <7>2, p. 158

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Articles3

More Articles
New antiarrhythmic agents. 7. 2,3-Diaminopropionanilides.

J. Med. Chem. 24(9) , 1059-63, (1981)

A series of 2,3-diaminopropionanilides was synthesized by acylation of mono- and disubstituted aniline derivatives with 2,3-dibromopropionyl chloride and subsequent amination with the appropriate seco...

Chiral synthesis of both enantiomers of 1, 4-dideoxy-1, 4-immolyxitol and 1, 4-dideoxy-1, 4-iminoribitol. Takano S, et al.

Tetrahedron Asymmetry 3(6) , 681-84, (1992)

Concise enantioselective synthesis of acromelic acid A. Takano S, et al.

J. Am. Chem. Soc. 109(18) , 5523-24, (1987)

 Synonyms

Propionyl chloride,2,3-dibromo
MFCD00000712
2,3-dibromo propanoyl chloride
1,2-dibromopropionyl chloride
chloroanhydride of 1,2-dibromopropionic acid
2,3-Dibromopropionyl chloride
EINECS 242-575-2