AZD9567

Modify Date: 2024-04-02 15:31:46

AZD9567 Structure
AZD9567 structure
Common Name AZD9567
CAS Number 1893415-00-3 Molecular Weight 494.53
Density N/A Boiling Point N/A
Molecular Formula C27H28F2N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AZD9567


AZD9567 (compound 15) is a potent, selective and oral active non-steroidal glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].

 Names

Name AZD9567

 AZD9567 Biological Activity

Description AZD9567 (compound 15) is a potent, selective and oral active non-steroidal glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].
Related Catalog
Target

IC50: 3.8 nM (Glucocorticoid receptor)[1].

References

[1]. Ripa L, et al. Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile. J Med Chem. 2018 Mar 8;61(5):1785-1799.

 Chemical & Physical Properties

Molecular Formula C27H28F2N4O3
Molecular Weight 494.53
Storage condition 2-8℃