(R)-2-Hydroxymethylpropanoic acid

Modify Date: 2024-01-04 10:50:50

(R)-2-Hydroxymethylpropanoic acid Structure
(R)-2-Hydroxymethylpropanoic acid structure
Common Name (R)-2-Hydroxymethylpropanoic acid
CAS Number 1910-47-0 Molecular Weight 104.104
Density 1.2±0.1 g/cm3 Boiling Point 252.9±23.0 °C at 760 mmHg
Molecular Formula C4H8O3 Melting Point N/A
MSDS N/A Flash Point 121.0±19.1 °C

 Use of (R)-2-Hydroxymethylpropanoic acid


(R)-3-Hydroxyisobutyric acid is an intermediate in the pathways of l-valine and thymine and plays an important role in the diagnosis of the very rare inherited metabolic diseases 3-hydroxyisobutyric aciduria and methylmalonic semialdehyde dehydrogenase deficiency.

 Names

Name (2R)-3-hydroxy-2-methylpropanoic acid
Synonym More Synonyms

 (R)-2-Hydroxymethylpropanoic acid Biological Activity

Description (R)-3-Hydroxyisobutyric acid is an intermediate in the pathways of l-valine and thymine and plays an important role in the diagnosis of the very rare inherited metabolic diseases 3-hydroxyisobutyric aciduria and methylmalonic semialdehyde dehydrogenase deficiency.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Podebrad F, et al. Stereodifferentiation of 3-hydroxyisobutyric- and 3-aminoisobutyric acid in human urine by enantioselective multidimensional capillary gas chromatography-mass spectrometry. Clin Chim Acta. 2000 Feb 25;292(1-2):93-105.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 252.9±23.0 °C at 760 mmHg
Molecular Formula C4H8O3
Molecular Weight 104.104
Flash Point 121.0±19.1 °C
Exact Mass 104.047340
PSA 57.53000
LogP -1.14
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.455

 Safety Information

HS Code 2918199090

 Customs

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

R-b-Hydroxyisobutyrate
R-β-Hydroxyisobutyric acid
3-hydroxy-2-methylpropionate
D-b-Hydroxyisobutyrate
(2R)-3-Hydroxy-2-methylpropanoic acid
Propanoic acid, 3-hydroxy-2-methyl-, (2R)-
oxy-isobutyric acid
R-b-Hydroxyisobutyric acid
3-hydroxyisobutyric acid
2-hydroxymethylpropionic acid
(R)-3-Hydroxy-2-methylpropionic acid
(R)-2-Hydroxymethylpropanoic acid
(R)-3-Hydroxyisobutyric acid