GSK6853
Modify Date: 2024-01-08 17:38:15
GSK6853 structure
|
Common Name | GSK6853 | ||
|---|---|---|---|---|
| CAS Number | 1910124-24-1 | Molecular Weight | 409.482 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 545.9±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H27N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 284.0±30.1 °C | |
Use of GSK6853GSK6853 is a potent and selective inhibitor of the BRPF1 bromodomain. shows excellent BRPF1 potency (pKd 9.5) andgreater than 1600-fold selectivity over all other bromodomainstested.target: BRPF1.[1]In vivo: The ip route of administration would be suitable for dosing GSK6853 in potential PK/PD models. [1] |
| Name | N-{1,3-Dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl}-2-methoxybenzamide |
|---|---|
| Synonym | More Synonyms |
| Description | GSK6853 is a potent and selective inhibitor of the BRPF1 bromodomain. shows excellent BRPF1 potency (pKd 9.5) andgreater than 1600-fold selectivity over all other bromodomainstested.target: BRPF1.[1]In vivo: The ip route of administration would be suitable for dosing GSK6853 in potential PK/PD models. [1] |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 545.9±50.0 °C at 760 mmHg |
| Molecular Formula | C22H27N5O3 |
| Molecular Weight | 409.482 |
| Flash Point | 284.0±30.1 °C |
| Exact Mass | 409.211395 |
| LogP | 0.98 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.621 |
| Storage condition | -20℃ |
| N-{1,3-Dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl}-2-methoxybenzamid |
| N-{1,3-Dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl}-2-methoxybenzamide |
| Benzamide, N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxy- |
| N-{1,3-Diméthyl-6-[(2R)-2-méthyl-1-pipérazinyl]-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl}-2-méthoxybenzamide |
| GSK6853 |