D-Mevalonolactone

Modify Date: 2025-08-26 09:22:00

D-Mevalonolactone Structure
D-Mevalonolactone structure
Common Name D-Mevalonolactone
CAS Number 19115-49-2 Molecular Weight 130.14200
Density 1.189g/cm3 Boiling Point 274.9ºC at 760 mmHg
Molecular Formula C6H10O3 Melting Point N/A
MSDS Chinese USA Flash Point 110ºC

 Use of D-Mevalonolactone


Mevalonolactone is a chemical that can be used in the preparation of a vitamin E.

 Names

Name (4R)-4-hydroxy-4-methyloxan-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.189g/cm3
Boiling Point 274.9ºC at 760 mmHg
Molecular Formula C6H10O3
Molecular Weight 130.14200
Flash Point 110ºC
Exact Mass 130.06300
PSA 46.53000
LogP 0.07440
Vapour Pressure 0.000662mmHg at 25°C
InChIKey JYVXNLLUYHCIIH-ZCFIWIBFSA-N
SMILES CC1(O)CCOC(=O)C1

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
HS Code 2932999099

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles27

More Articles
Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones.

Bioorg. Med. Chem. 17(23) , 7915-23, (2009)

A novel series of 2-cyclopropyl-4-thiophenyl quinoline-based mevalonolactones were synthesized from the substituted anilines by several reactions. Among them, (4R,6S)-6-[(E)-2-(2-cyclopropyl-6-fluoro-...

Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS.

J. Lipid Res. 48(5) , 1212-20, (2007)

We have developed a new sensitive and specific nonradioisotope assay method to measure the activity of HMG-CoA reductase, the rate-controlling enzyme in the cholesterol biosynthetic pathway. This meth...

Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS.

Anal. Biochem. 329(1) , 28-34, (2004)

We present an integrated consolidation of previously reported methods for screening hydroxymethylglutaryl-coenzyme A reductase (HMGR) inhibitors in 96-well microtiter plates with rapid workup using es...

 D-MevalonolactoneBioassay

View more

Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100
Name: Contractile Force Screening of Prestwick Library for asthma drug discovery
Source: 24015
Target: N/A
External Id: HSPH_Screening_CFS_001
Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750
Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE
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 Synonyms

D-Mevalonic Acid Lactone
D-Mevalonolactone
Adeka mevalonolactone
mevalonic lactone
Mevalonic-D,L acid lactone
Prestwick_97
MFCD01074894
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