NTNCB hydrochloride

Modify Date: 2025-08-24 21:31:44

NTNCB hydrochloride Structure
NTNCB hydrochloride structure
Common Name NTNCB hydrochloride
CAS Number 191931-56-3 Molecular Weight 508.073
Density N/A Boiling Point N/A
Molecular Formula C25H34ClN3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NTNCB hydrochloride


NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5[1].

 Names

Name NTNCB hydrochloride
Synonym More Synonyms

 NTNCB hydrochloride Biological Activity

Description NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5[1].
Related Catalog
Target

hY5 receptor:8 nM (Ki)

hY1 receptor:16032 nM (Ki)

References

[1]. Islam I, et al. Discovery of potent and selective small molecule NPY Y5 receptor antagonists. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1767-9.

 Chemical & Physical Properties

Molecular Formula C25H34ClN3O4S
Molecular Weight 508.073
Exact Mass 507.195862
Storage condition -20°C

 Synonyms

Benzenesulfonamide, 2-nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1)
2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride
2-Nitro-N-[(trans-4-{[(1,2,3,4-tetrahydro-2-naphthalenylmethyl)amino]methyl}cyclohexyl)methyl]benzenesulfonamide hydrochloride (1:1)
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