(±)-H3RESCA-TFP

Modify Date: 2024-01-04 19:40:16

(±)-H3RESCA-TFP Structure
(±)-H3RESCA-TFP structure
Common Name (±)-H3RESCA-TFP
CAS Number 1919794-40-3 Molecular Weight 584.51
Density N/A Boiling Point N/A
Molecular Formula C27H28F4N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (±)-H3RESCA-TFP


(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine)[1].

 Names

Name (±)-H3RESCA-TFP

 (±)-H3RESCA-TFP Biological Activity

Description (±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine)[1].
Related Catalog
In Vitro The aluminum fluoride restrained complexing agent (Al18F-RESCA) method combines the chemical advantages of a chelator-based radiolabeling method with the unique physical properties of the radionuclide of choice, fluorine-18. Proteins of interest can be conjugated to RESCA via amine coupling using (±)-H3RESCA-TFP. Al18F-labeled proteins can be obtained with moderate (12-17 GBq/µmol) to good (80-85 GBq/µmol) apparent molar activity, depending on the starting activity of 18F-[1].
References

[1]. Cleeren F, et al. Direct fluorine-18 labeling of heat-sensitive biomolecules for positron emission tomography imaging using the Al18F-RESCA method. Nat Protoc. 2018 Oct;13(10):2330-2347.

 Chemical & Physical Properties

Molecular Formula C27H28F4N2O8
Molecular Weight 584.51
Storage condition 2-8°C
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